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Lost是目前美国最受欢迎的电视剧之一，并曾荣获艾美奖最佳剧情类电视剧奖。
故事从一位职业医生Jack的视角展开，主要讲述一架客机坠落在太平洋的孤岛上，共48名乘客侥幸生还。起初，人们庆幸生还，期盼救援部队的到来，他们慢慢发现这个小岛似乎曾经来过和他们一样的人们，他们的求救信号已经不停的播发了16年，但是，似乎没有人发现他们的存在……
在渐渐的生存交往过程中，大家开始互相依赖。然而，每个人都有不可告人的秘密...生还者形形色色，国籍、人种、文化背景、个性各异，14位主演中有兄妹，有父子，有朋友，有夫妻，也有敌人。他们既要克服恶劣的天气，在荒蛮的热带丛林中寻找食物、水源，还有一只在夜晚发出令所有人心惊胆战叫声的神秘生物；不断地有人神秘失踪和死亡...
而当岛上的秘密一个个被揭开的同时，又出现一串串新的疑问。The others，Dharma组织，肃清，Jacob... 越来越多的疑团使观众也不禁迷失在《迷失》中。扣人心弦、一环扣一环的悬念，博学广大的知识涉及面，演员精湛出色的演技，以及发人深省的人生感悟，共同促成了这部经典大剧！
After Oceanic Air Flight 815 tears apart in mid-air and crashes on a Pacific island on September 22nd 2004, its survivors are forced to find inner strength they never knew they had in order to survive. But they discover that the island holds many secrets, including a mysterious smoke monster, polar bears, housing with electricity and hot & cold running water, a group of island residents known as "The Others," and a mysterious man named Jacob. The survivors also find signs of those who came to the island before them, including a 19th century sailing ship called The Black Rock and the ruins of an ancient statue, as well as bunkers belonging to the Dharma Initiative -- a group of scientific researchers who inhabited the island in the recent past.
